STABILITY INDICATING HPLC-ECD METHOD FOR THE ANALYSIS OF CLARITHROMYCIN IN PHARMACEUTICAL DOSAGE FORMS: METHOD SCALING VERSUS RE-VALIDATION

Stability Indicating HPLC-ECD Method for the Analysis of Clarithromycin in Pharmaceutical Dosage Forms: Method Scaling versus Re-Validation

An isocratic high-performance liquid chromatographic method using electrochemical detection (HPLC-ECD) for the quantitation of clarithromycin here (CLA) was developed using Response Surface Methodology (RSM) based on a Central Composite Design (CCD).The method was validated using International Conference on Harmonization (ICH) guidelines with an an

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Epidemiology and molecular characterization of Staphylococcus aureus causing bovine mastitis in water buffaloes from the Hazara division of Khyber Pakhtunkhwa, Pakistan.

Buffalo represent a major source of milk in Pakistan.However, production is impacted by the disease bovine mastitis.Mastitis causes significant economic losses, with Staphylococcus aureus (S.aureus) being one of its major causative agents.While much work has been done understanding the epidemiology of bovine mastitis in Pakistan, detailed molecular

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